PhosphoSTAT3 (pSTAT3), phosphoSTAT1 (pSTAT1), suppressor of cytokine signaling-3 (SOCS3), protein inhibitor ... 3-kinase (PI3K)/serine/threonine kinase or protein kinase B (AKT) signalling pathway.15 ...
LIN treatment decreased the expression of muscle RING-finger protein-1 (MuRF1) and Atrogin1(MAFbx) in muscle, and the activation of insulin-like growth factor-1 (IGF-1)/protein kinase B (Akt)/forkhead ...
ATAC-seq and RNA-seq analysis reveals that AurA inhibition restricts chromatin accessibility of genes associated with inflammatory pathways such as JAK-STAT ... AurA inhibition reduced the activation ...
The activity of insulin-like growth factor-1 (IGF-1)/protein kinase B (PKB/AKT) pathway in SM was detected by western blotting test. Results: OVA exposure caused obvious AAI and poor PF in adolescent ...
One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...
Figure. Schematic diagram depicting signaling pathways for regulation of phospho-Ser473-Akt activity cell survival by PHLPP-1. Site-specific dephosphorylation of Ser473-Akt, but not Thr308-Akt by ...
The wide neuroprotective effects of S1R agonists are achieved by a variety of pro-survival and antiapoptotic S1R-mediated signaling functions ... we also explained how the dysregulation of these ...
In addition, it identifies angiogenic myocardial signaling as a potential target of antihypertrophic interventions in hypertension. Moderate Exercise Preferentially Activates Phosphatidylinositol ...
Department of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, China ...