RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns, splicing ...

Collectively, these results demonstrate that TSSC4 deficiency leads to aberrant alternative splicing and increased expression of oncogenes, further supporting the role of TSSC4 as a tumor suppressor.

Using a general linear mixed effects regression model (GLMM), we leverage variation across 10,295 tumors from 33 cancer types and find that complexes that re-fold proteins (chaperones), degrade ...

You’ve reached your account maximum for followed topics. A recent Diablo 4 patch significantly boosted the drop rate of Aberrant Cinders. One player managed to earn a whopping 5,858 Aberrant ...

Abstract and Introduction Aberrant Splicing of Hyaluronan Synthase 1 in Waldenström's Macroglobulinemia Genetic Variations in Genomic DNA Might Promote Splicing Within HAS1 Sequential Acquisition ...

Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host genes. Although these splicing-regulated genes are ...