Bayer says menopause drug succeeds in breast cancer study
The results suggest Bayer’s elinzanetant may help a broader group of women with vasomotor symptoms, which are associated with ...
pharmaphorum5d
Astellas breaks new ground in menopause with Veozah
whose NK1,3 antagonist elinzanetant is in late-stage clinical development. Both drugs are thought to work by binding to and blocking the activities of NK receptors that play a role in the brain ...
gut.bmj2d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
gut.bmj4d
Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis
Objective Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory ...
Frontiers5d
A novel approach to completely alleviate peripheral neuropathic pain in human patients: insights from preclinical data
Various classes of drugs, including tricyclic antidepressants (amitriptyline and nortriptyline), serotonin-norepinephrine reuptake Inhibitors (duloxetine and venlafaxine), N-methyl-D-aspartate (NMDA) ...
The New York Times5d
What’s Going On in This Picture?
Look closely at this image, stripped of its caption, and join the moderated conversation about what you and other students see. By The Learning Network Look closely at this image, stripped of ...
The EMBO Journal5d
Oncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors
Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell ...