Phys.org28d
Atomic force microscopy reveals microtubule defects at submolecular resolution
The α-tubulin and β-tubulin monomers of the protofilaments ... arrangement of protofilaments and consequently impair the functions of MTs. The study also explored MT interactions with Taxol ...
EurekAlert!29d
Exploring microtubule lattice at submolecular resolution
MTs are composed of α-tubulin and β-tubulin proteins ... revealing potential for advancing drug discovery. Understanding MT function and protein interactions can guide the development of ...
C&EN1mon
Visualizing the Submolecular Organization of αβ-Tubulin Subunits on the Microtubule Inner Surface Using Atomic Force Microscopy
Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan ...
eLife1mon
PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Research Unit of Oral Carcinogenesis and Management & Chinese Academy of ...
eLife4y
Cryo-EM structure of VASH1-SVBP bound to microtubules
The dynamic tyrosination-detyrosination cycle of α-tubulin regulates microtubule functions. Perturbation of this cycle impairs mitosis, neural physiology, and cardiomyocyte contraction. The ...