Investigations Physical examination, laboratory testing, X-rays of the hands, feet and pelvis, CT of the pelvis, microscopic analysis of an aspirate from a finger tophus. Diagnosis Tophaceous gout ...

When your body produces too much uric acid and fails to eliminate it effectively, it can lead to health issues such as high or low uric acid levels.

Tophus Formation: In severe cases, swollen growths known as tophi may develop around joints such as the knees, wrists, fingers, feet, ears, and the Achilles tendon. There are many ways one can ...

Dual-energy CT (DECT) scans were taken from all patients before the first infusion and after the last infusion. Computerised tophus volumes were calculated for the baseline and follow-up assessments ...

CT scans were scored for the presence and diameter of bone erosions and tophi. The presence of intraosseous tophus (tophus visualised within bone) was recorded. The relationships between radiographic ...

All involved apophyseal joints were eroded (figure 1). No vertebral bone erosion was observed. Calcification of spinal tophus was observed in 4 patients. DECT identified peripheral deposits in 15/18 ...

Uric acid is a waste product in the body. However, sometimes it can build up in the joints and tissues, causing a range of health problems. Doctors say gout flares often start suddenly at night ...

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Gout is one of the most severe and frequent rheumatic diseases. Clinical manifestations of gout arise from uric acid crystal deposition in the musculoskeletal tissue. At high concentrations of uric ...