38 Nevertheless, studies using proteomic analysis have confirmed AKT phosphorylation in FL samples, which is indicative of PI3K pathway activation. 39,40,42,43 Additional evidence for the ...
deriving elephant iPSCs proved challenging because these animals have a complex gene pathway not found in other species. The researchers overcame this by suppressing core genes called TP53 that ...
Key mutations were observed in TP53 and ARID1A genes and TP53 pathway was downregulated in patients with primary treatment resistance. A high-risk signature based on the identified molecular ...