The nation's blood supply is facing a critical shortage due to a combination of factors, including a drop in donors during the holiday season.

When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the hemoglobin protein causes the red blood cells to lose oxygen and warp into a sickle shape during periods of ...

A once-groundbreaking sickle cell disease drug — at the center of a $5.4 billion acquisition two years ago — is the subject ...

The following is a summary of “Safety and efficacy of mitapivat in sickle cell disease (RISE UP): results from the phase 2 ...

so they have a mixture of normal and sickle red blood cells. In most situations, individuals who are heterozygous for sickle-cell anemia are phenotypically normal. Under these circumstances ...

But in people with weakened immune systems or sickle cell disease, the virus can lead to more severe symptoms, such as a significant drop in red blood cell production (anemia). If a pregnant woman ...