Following oral administration of a drug, extent and speed of absorption ... Ibuprofen is a relatively weak acid (pka 4.4) and its solubility in water or at acid pHis very low.

Drug solubility may be reduced at neutral pH compared ... Clopidrogel must be metabolized in the liver by CYP2C19 (CYP3A4) to its active form. The antiplatelet effect of clopidrogel varies among ...

To design safe and effective drugs, the pharmacology of how drugs work in relationship to the body must be understood. This ...

A team of University of Melbourne researchers from the Caruso Nanoengineering Group has created an innovative drug delivery ...

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research ...

Salt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volume, which can have serious, sometimes deadly, health consequences.

Liam Payne’s drug usage brought him “close to death” multiple times months before his fatal fall in October, according to his friend Roger Nores. In a 91-page filing obtained today by ...

BEIRUT (AP) — Syria’s nearly 14-year-old civil war fragmented the country, crumbled the economy and created fertile ground for the production of the highly addictive drug Captagon. Militias ...

The collective discussions and knowledge of these scientists contributed to the publication of this report, which will help improve drug development, and also contribute to the foundations of ...

The field of oncology has witnessed remarkable progress in the treatment of solid tumors, yet the quest for optimal therapeutic outcomes remains a ...