As noted above, stellate cell activation is the central ... matrix protease activity play an important role in ECM remodeling accompanying fibrosing liver injury (see section on Extracellular ...

First, the large liver mass, via the reticuloendothelial function of the Kupffer cells, is thought to be capable of sequestering cytotoxic antibodies formed against the graft. The presence of a ...

Activation of Kupffer cells (liver-resident macrophages ... A notable focus of the review is the role of extracellular vesicles (EVs) in intercellular communication. These nanoscale particles ...

Kupffer cells (KCs) also contribute to this inflammation ... The review examines how alcohol metabolism affects liver function, focusing on the roles of oxidative stress and inflammation in ...

Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has ...

Discover how liver cancer evades the body's natural defenses and explore the link between fatty liver disease and increased ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors.