Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

In eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than the simple assembly of amino acids in ribosomes. Nearly ...

University of Würzburg researchers identified a fast mRNA degradation mechanism driven by m6A modifications. This process ...

To overcome these challenges, a research team including specially appointed Associate Professor Hiroshi Kadokura and Professor Hideki Taguchi from the Institute of Science Tokyo, Japan, developed an ...

The researchers discovered that the RNAP transcribing the mRNA deploys two different anchors to rope in the ribosome and ensure a solid footing and start of protein synthesis. This is similar to a ...

"The ribosome first moves slowly ... can be coordinately regulated using the basics of the genetic code and protein synthesis in an unanticipated and complex manner. The new regulatory mechanism ...

LMU scientists show how bacteria control their protein biosynthesis through cell metabolism – possible approach for developing novel therapies.

This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...