Puzzles can take many forms, whether it be about shapes, instructions, physics, and/or portals. As time passes, the best puzzle co-op games will continue to evolve and grow. Updated on December 26 ...

But perhaps most importantly, the game’s developers at MachineGames rarely use puzzles to bar your progress, reserving the most difficult scenarios as optional objectives that you can return to ...

The jungles of Siam are hiding all sorts of secrets, and scattered across it is a series of puzzles that might just be the hardest in the entire game. When you first find the hidden pyramid as par ...

In this work, the authors develop mirror-image monobodies (Mb) made of D-amino acids against the BCR::ABL1 SH2 domain with high binding affinities. The heterochiral Mb-SH2 structures reveal an ...

Jigsaw puzzles come in many shapes and sizes and can be anything from just a few pieces to several thousand. The earliest jigsaws appeared in the 1760s when European mapmakers pasted maps onto pieces ...

Puzzle games. They’ve been around since the beginning, appealing to those who want a challenge in their games beyond “shooting everything in sight” or “figuring out your RPG team lineup.” ...

Chris Danner and Elms Puzzles cutter (and co-owner) Shay Carmichael on all things jigsaw, from choosing the perfect puzzle to involving your puzzle-averse pals. When choosing a puzzle, you don’t ...

Test your mettle with this puzzle created exclusively for "Smithsonian" readers Test your mettle with this puzzle created exclusively for 'Smithsonian' readers Test your mettle with this puzzle ...