A Stanford-led team discovered a new ketosis pathway involving BHB-amino acids, shedding light on its effects like appetite ...

Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby ...

Within minutes of fertilization, the egg of a fruit fly becomes a scene from the battle of the sexes. The egg attacks and destroys the cellular “power plants,” or mitochondria, from the sperm that had ...

Fewer cows on the farm and a broader range of farming practices, including involvement in the emerging alternative proteins ...

Researchers have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment of cancer.

In this manuscript, Yao et al. present solid evidence to show that MnMYL3 may serve as a receptor for NNV via macropinocytosis. This manuscript is valuable for understanding the molecular mechanisms ...

Researchers at the University of Würzburg have discovered a process that breaks down mRNA molecules in the human body ...

University of Würzburg researchers identified a fast mRNA degradation mechanism driven by m6A modifications. This process ...

Endocrine therapy against the estrogen receptor (ER) is widely used for the treatment of ER+ breast cancer. Selective estrogen receptor degraders (SERDs) compete directly with estrogen for ER binding ...

Baylor College of Medicine has disclosed proteolysis targeting chimeras (PROTACs) comprising cereblon (CRBN) ligands coupled to Bruton tyrosine kinase (BTK)-, DNA-binding protein Ikaros (IKZF1)- and ...

mediating the signaling pathways for protein degradation and the maintenance of cellular homeostasis. These proteins act as ...

Degradome sequencing, also known as parallel analysis of RNA ends (PARE) sequencing, is a cutting-edge technique that leverages high-throughput sequencing and bioinformatics to investigate the ...