A needle biopsy revealed normal liver architecture, with variations in the appearance of individual cell nuclei, some appearing ... amounts of portal connective tissue with bile-duct proliferation ...

In the present manuscript So et al describe an optimized method for nuclei isolation and single nucleus RNA sequencing (snRNA-Seq), which they use to characterize cell populations in lean and obese ...

He explains, "We were measuring tissue stiffness in the zebrafish retina, and realized that it depended on the packing of nuclei. This was totally unexpected because tissue mechanics is believed ...

Its single-cell RNA and nuclei isolation supplies aim to sort out and label complex cell mixtures—ranging from 100 cells up to 1 million—without needing additional microfluidic consumables ...

One to twenty-four samples can be processed in a single run to isolate free-circulating DNA from fetal-originated DNA in ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

An international research team has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering. An international research team ...

RNA extraction presents unique challenges, as yields can vary widely based on the type of tissue being processed. For instance, fibrous tissues may require prolonged lysis times to achieve effective ...

To determine pathological changes in tissues, immunohistochemical studies ... the intensity of staining is analyzed and the percentage of stained nuclei is estimated. H-score is widely used ...