Mirum Pharmaceuticals, Inc. today provided its preliminary and unaudited estimates for full-year 2024 net product sales, year-end cash balance, corporate updates, and full-year 2025 outlook. "2024 ...

AIM To time the onset of cytomegalovirus (CMV) infection in patients (n=39) with CMV associated neonatal cholestasis by analysing CMV DNA on Guthrie cards sampled at 3 days of age. METHODS CMV ...

Cholestasis, the most consistent feature, was present in each case. Each of the three infants who survived beyond the immediate neonatal period had hepatic parenchymal damage with focal necrosis.

Progressive familial intrahepatic cholestasis (PFIC) is a rare genetic condition that prevents bile from properly draining from the liver. It often begins in infancy. PFIC can cause a range of ...

The combination of arthrogryposis, renal dysfunction and cholestasis led to the suspicion of arthrogryposis, renal tubular dysfunction, cholestasis (ARC) syndrome, which was then proved by genetic ...