However, a direct role of UCP-2 in the development of liver injury could not be confirmed in experimental models of fatty liver using a UCP-2 knockout mouse. [52] Mitochondrial injury can lead to ...

Weight loss has become a major focus for many, with new solutions like Ozempic gaining popularity for their effectiveness in ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously called non-alcoholic fatty liver disease, is a ...

This editorial reviews the impact of phytochemicals on metabolic diseases, emphasizing their potential in reducing ...

and secretion as very-low-density lipoprotein (VLDL), mitochondrial β/3-oxidation, and enzymatic removal of lipid peroxidation products. The nuclear receptor PPAR-α plays a central role in ...

In today’s fast-paced world, maintaining optimal health and performance is paramount. Many seek natural solutions to enhance ...

This protein is linked to metabolic diseases with an inflammatory background: for example, insulin resistance induced by obesity or diabetes, dyslipidaemia or metabolic fatty liver disease (MASLD)." ...

New Research in Fatty Liver Disease Aims to Help With Early ... has now been able to show in mice that adaptations in the liver mitochondria take place after only a few ... Identifying a New ...

1 to establish an in vitro model of NAFLD in our study. The lipid accumulation in cells and the morphology of mitochondria and autolysosomes were observed by Oil Red O staining and transmission ...

The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...