However, a direct role of UCP-2 in the development of liver injury could not be confirmed in experimental models of fatty liver using a UCP-2 knockout mouse. [52] Mitochondrial injury can lead to ...
This discovery could improve our understanding of chronic liver diseases like alcohol-associated liver disease (ALD) and ...
The latter group, common between both ALD and NAFLD, includes the main mitochondrial ROS scavenger manganese-dependent superoxide dismutase (SOD2) and genes that influence the relative abundance ...
"The interaction between the lipid droplets (LD) and the mitochondria is functionally important for the homeostasis of the ...
The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...
If approved, semaglutide would be only the second drug FDA-approved to treat fatty liver disease ... way cells make energy in structures called mitochondria. “The miracle of GLP-1,” he ...
These studies include age-related neurodegeneration such as dementia and obesity-associated disorders such as nonalcoholic fatty liver disease ... the role of mitochondrial dysfunction during ...
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