In this manuscript, Yao et al. present solid evidence to show that MnMYL3 may serve as a receptor for NNV via macropinocytosis. This manuscript is valuable for understanding the molecular mechanisms ...
The biotech had been testing sevasemten, an orally administered fast skeletal myosin inhibitor, in a trial of 40 adults and 29 adolescents with Becker muscular dystrophy. Edgewise described the ...
In this review, we highlight three key areas of molecular dysregulation directly underlying impaired cardiac relaxation in HFpEF: altered calcium sensitivity in the troponin complex, impaired ...