We describe aspirin as a cyclooxygenase inhibitor, atorvastatin as a 3-hydroxy-3-methylglutaryl (HMG) coenzyme A reductase inhibitor, and lithium as a glycogen synthase kinase 3β (GSK3β ...

S13 One of the mechanisms of this ‘renal dyslipidaemia’ may be the increase in hepatic LDL synthesis that results from urinary protein loss causing upregulation of 3-hydroxy-3-methylglutaryl CoA ...

Objective: To explore the impact of statin use on cognition. Data Sources: A literature search was performed using MEDLINE (1950-November 2011), EMBASE (1980-November 2011), and the Cochrane ...

He, H.J., Cen, X.H., Liang, Y.J., Zhong, J.M., Deng, J.H. and Jiang, Y.J. (2025) Progress in the Regulation of Lipid Metabolism by the Orphan Nuclear Receptor Nur77. Journal of Biosciences and ...

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada (C.S., K.J.R). Centre for Infection, Immunity ...

Sirtuins, identified as (NAD +)- dependent class III histone deacetylases, engage in a spectrum of biological functions, encompassing DNA damage repair, oxidative stress, immune modulation, ...

Around 40% of all patients undergoing angiography are found to have normal coronary arteries or non-obstructive coronary artery disease (NOCAD). Despite the high prevalence, this is a group who rarely ...

Hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, also called statins, are commonly prescribed medications that lower serum cholesterol and decrease cardiac morbidity and mortality.

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

Alonso has received honoraria fees by participating in an advisory board and symposia for Tecnofarma and Sanofi. Mata has received a research grant from Amryt Pharma Plc. The other authors have ...