A lipid anchor on nerve cell membranes stabilizes prion proteins (PrPC) and prevents their pathological aggregation into forms linked to prion diseases.
Researchers at Ruhr University Bochum discovered that a lipid anchor on nerve cell membranes stabilizes prion protein folding ...
Protein aggregation is typical of neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as ...
Researchers have gained valuable insight into the development of prion diseases of the brain.Protein aggregation is typical of various ...
The collection of proteins within a cell determines its health and function. Proteins are responsible for nearly every task of cellular life, including cell shape and inner organization ...
Therefore, the collection of lipids and proteins that make up a cellular ... many proteins are not free to move. They are often anchored in place within the membrane by tethers to proteins outside ...
Engagement of a GPI-anchored protein creates signaling rafts from smaller, transient, lipid rafts: Although membrane domain/rafts are implicated in receptor-mediated signaling and protein trafficking, ...
The privately-held company, which launched this week with a $52 million Series A financing, plans to develop oncology drugs that target specific lipid-binding pockets on proteins. Tasca ...
Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...
Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer’s, Parkinson’s and prion diseases such ...