One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

Together with his team, they discovered Inceptor in 2021 and described its role as an inhibitor of the insulin signaling pathway. Both Inceptor and the insulin receptor are located on the surface ...

Dopamine receptors bind dopamine, insulin receptors bind insulin ... through a sequence of molecular switches to internal signaling pathways. Membrane receptors fall into three major classes ...

Insulin-like growth factors (IGFs) released by regenerating limbs and hepatic insulin signaling pathways are key to help adapting lipid metabolism to meet the needs of cell proliferation.

A study by researchers at Wayne State University links exposure to air pollution to an increased risk of type 2 diabetes.

This heightened activity disrupts normal insulin signaling, contributing to the ... modification and establishes a structured enzymatic pathway. The team’s experiments also revealed that SCAN ...

Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...

Insulin resistance refers to impaired insulin ... This not only adds to our understanding of biology and signaling pathways in cells, but, more importantly, it is leading to exciting new ...

A study by researchers at Wayne State University has found a strong connection between air pollution exposure and an ...

Joan Massagué, PhD, a world leader in research on signaling pathways and transcriptional programs that ... where he worked on mechanisms of insulin action. Later that year, he became assistant ...