Here, the authors show that the CPSF6-RARG (CR) fusion interacts with histone deacetylase 3 (HDAC3) to promote myeloid transformation and HDAC inhibitors reduce CR-associated leukemia in ...

Department of Pharmaceutical and Cell Biological Chemistry, Pharmaceutical Institute, University of Bonn institution, An der Immenburg 4, Bonn 53121, Germany ...

In Ecotoxicology and Environmental Safety, researchers highlight a multitude of studies on endocrine disrupting chemicals ...

The list includes several groundbreaking therapies that are expected to change the treatment landscape for several diseases and conditions.

This study reveals how acetylation and deacetylation of SNAP47 control fusion by modulating HOPS recruitment.