Mesenchymal stem cells (MSCs), or mesenchymal stromal cells, are a non-hematopoietic group of cell precursors that originate from mesoderm and ectoderm ... “spindle-shaped proliferating cells ...

Notch inhibits the differentiation of cardiomyocytes from mesoderm in embryos and embryonic stem cells. Notch and/or its target genes of the Hes-related transcription factor (Hrt) family are ...

The team has unveiled an innovative technique to convert fibroblasts—common connective tissue cells—into mature and functional induced cardiomyocytes (iCMs). Their method relies on combining ...

The team has unveiled an innovative technique to convert fibroblasts - common connective tissue cells - into mature and functional induced cardiomyocytes (iCMs). Their method relies on combining ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease-related ...

The pelviperineal organs of the female reproductive tract form an essential cornerstone of human procreation. The system comprises the ectodermal external genitalia, the Müllerian upper-vaginal, ...

A more commonly used and reliable immunostaining marker selective for rat and human PSC (and absent in fibroblasts) is glial fibrillar acidic protein. Some researchers have reported the absence of ...

Newly generated human embryonic stem cell‐derived atrial‐like cardiomyocytes resemble human atrial cardiomyocytes and prove to be a valuable model for pre‐clinical drug screenings to identify ...

Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan ...