Increased matrix production is the most direct way that stellate cell activation generates hepatic fibrosis. The most potent stimulus to collagen ... and fibroblast activation protein; [38 ...

Idiopathic pulmonary fibrosis (IPF ... surface that promotes interactions with fibroblast cells on the outside of the lungs, ...

The process by which lung injury either leads to healing or fibrosis relies in part on what happens to a cell called a ...

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease marked by the thickening and scarring of lung tissue with unclear etiology. Affecting around five million people ...

Inhibiting the HIF2 protein was found to promote repair processes in a mouse model of lung injury, and may be a strategy for ...

The study was recently published in Science Translational Medicine and showed how dextromethorphan can impede the collagen that forms scars, inside cells, reducing lung fibrosis. Lung fibrosis ...

RS BioTherapeutics, whose mission is to develop life-changing medicines for the millions of people suffering from deadly lung diseases characterized by pulmonary inflammation, is pleased to announce ...

Scleroderma is an autoimmune connective-tissue disease whose hallmark is excessive collagen deposited around capillaries and in affected tissues, such as the skin, lungs, kidneys, and esophagus.