Peptides, as versatile biological molecules, have garnered significant attention in scientific research due to their ...
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disorder driven by unrelenting extracellular matrix deposition. Fibroblasts are recognized as the central mediators of extracellular ...
Quantitative and qualitative changes in matrix protease activity play an important role in ECM remodeling accompanying fibrosing liver injury (see section on Extracellular Matrix Degradation ...
1 Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China 2 Department of Pancreatic Surgery, West China ...
Stromal fibroblasts also contribute to this process by secreting extracellular matrix proteins, cytokines and additional growth factors that stimulate epithelial cell growth and aid in the ...
Fibroblast-specific Tcf21 gene–deleted mice demonstrate ... sustained TCF21 expression prevents the induction of genes associated with fibrosis and ECM (extracellular matrix) organization.
Former EN1-expressing cells give rise to a subpopulation of fibroblasts that has a high capacity for extracellular matrix production in adult murine skin. The role of EN1 in systemic sclerosis (SSc) ...
Interleukin (IL)-1 induced extracellular signal-regulated kinases (ERK) phosphorylation and matrix metalloproteinase-3 production ... IL-1 receptor (IL1R1) staining on wild-type, sdc4 and IL1R1 ...
The brain extracellular matrix plays a critical role in synaptic plasticity, including experience/adaptive-based changes in ...
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