Longevity Breakthrough: Scientists Restore “Youthful” Enzyme Activity To Combat Aging
Innovative therapies revive a once-undruggable mitochondrial aging regulator through a revolutionary enzyme activation ...
Frontiers18d
ProAD – A database of rotary ion-translocating ATPases in prokaryotic genomes
In many prokaryotes, the enzyme functions in reverse ... F-ATPases found in many bacteria and eukaryotic organelles (mitochondria, chloroplasts), V-ATPases typical for plasma or vacuolar membranes of ...
technologynetworks18d
Sweet Spot of Mitochondrial Mutations Fuels Cancer Growth
They linked this effect to pyruvate dehydrogenase, a key enzyme in cellular respiration. These findings uncover an important connection between mitochondrial DNA mutations and cancer metabolism.
C&EN19d
Mitochondria-Targeted DNA-Based Nanoprobe for In Situ Monitoring of the Activity of the mtDNA Repair Enzyme and Evaluating Tumor Radiosensitivity
New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China ...
AlphaGalileo24d
Glucose-6-phosphate dehydrogenase regulates mitophagy by maintaining PINK1 stability
Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy ... Among several hundreds of positive hits, they focused on one important enzyme, glucose-6 ...