(a) The basic elements of FISH are a DNA probe and a target sequence. (b) Before hybridization, the DNA probe is labeled by various means, such as nick translation, random primed labeling ...
CORRECTION: We regret that in the above Editorial (shown as it appears in print), Dr Eberwine's method for producing hybridization probes for DNA chips is described incorrectly. It is stated that ...
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel ...
All steps of ISH – from pre-hybridization to additions of probes, hybridization, stringency washes and antibody-mediated chromogenic or fluorescent reaction – are carried out by the robotic system.
In this regard, differentially labelled and reference DNA undergo co-hybridization to normal human metaphase chromosomes.
In contrast to other in situ hybridization (ISH) methods, this technique uses fluorescently labeled probes to detect specific ...