Missense mutations in histones can drive oncogenesis ... the H3 N-terminal tail disrupt repressive chromatin domains, alter gene expression, and in one case impair differentiation via reduction ...

Among 75 affected patients, who were not obviously related probands with a positive family history, nine had missense mutations in SOD1. Four of the nine probands carry the same R115G mutation in exon ...

Before species go extinct, their populations often shrink and become isolated. Healthy populations tend to have a large gene ...

Scientists at UC San Diego find that gene expression is linked to gene mutations and may be caused by them. That could make ...

The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to the Vanderbilt University Medical Center study ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches—gene therapy and ...

A gene-edited mouse with two male parents has survived to adulthood, pushing new progress on stem cell research.

A significant advancement in knowledge of the link between cognition and genetics has been made thanks to a study led by ...

The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new study.

A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can predict which ...