An international team of researchers has taken an important step toward understanding how gene expression is controlled ...

Leveraging extensive expertise in E3 ligases together with proprietary DNA-encoded libraries ... Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases ...

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College ...

Dysregulated functions of E3 ubiquitin ligases have been linked to many diseases, including T2DM and NAFLD, making them potential targets for drug development. The potential of developing therapeutic ...

They applied the new method to more than 1,500 European genomes (a person's complete set of DNA) from people who lived primarily during the first millennium AD (year 1 to 1000), encompassing the ...

Americans with European heritage have long been able to pinpoint their ancestry through DNA testing ... That's just a function of who we are as African Americans." About 5% of people who identify ...

Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Institute of Developmental Biology and Regenerative Medicine, College of Chemistry and ...

PrimeSTAR Max DNA Polymerase, T4 DNA ligase, T4 polynucleotide kinase, restriction endonucleases, and protein markers were purchased from TaKaRa (Dalian, China). Ampicillin, G418 sulfate, and plasmid ...

The predominant way in which conventional chemotherapy kills rapidly proliferating cancer cells is the induction of DNA damage. However ... they depend on the functions and mechanisms of action of EMT ...