Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially ...

Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are ...

Organoids are 3D cell culture ... 2D cell culture methods. Generally derived from stem cells, organoids can be generated using a support matrix and a cocktail of specific growth factors. The creation ...

Here, we developed an enhanced Caco-2/HT29-MTX-E12 co-culture model incorporating ... of differentiated intestinal epithelial monolayers (Ferraretto et al., 2018), maintaining stable organization with ...

Here, in bone marrow transplantation and organoid culture models, T-cell-derived Interferon-γ is shown to promote STAT1-dependent intestinal stem cell c-MYC expression and epithelial regeneration.

For an up-to-date version of the latest best practices for single-cell RNA-seq analysis (and more modalities ... practices established in the manuscript are applied to a mouse intestinal epithelium ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell ... 5 days after plating. Co-culture of Isolated ISCs and ...

In the nude mouse ... epithelial cell line MCF10A (CRL-10317, ATCC, Manassas, VA, United States) was cultivated on a collagen-coated dish in HuMEC (Gibco, Thermo Fisher Scientific, Waltham, MA, United ...

Treatment with ω-3 PUFAs is associated with a reduction in measures of mucosal epithelial cell ... in a mouse model of infection-induced colitis-associated cancer.57 The dose–response relationship ...

With every bite of food we take, our intestinal immune system must make a big decision. Tasked with defending us from foreign ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...