Mitosis, the fundamental process by which cells divide, ensures the accurate distribution of genetic material to daughter ...

During mitosis, many of the spindle fibers attach ... Prometaphase is an extremely dynamic part of the cell cycle. Microtubules rapidly assemble and disassemble as they grow out of the centrosomes ...

it must grow and make copies of all the organelles such as mitochondria and ribosomes. The cell must also replicate the chromosomes in the nucleus, then it can divide by mitosis.

Another important checkpoint takes place later in the cell cycle, just before a cell moves from G 2 to mitosis. Here, a number of proteins scrutinize the cell's DNA, making sure it is structurally ...

Our investigators have also shed light on how changes in the cell cycle — the cycle in which cells grow and divide — push normal cells toward cancer. Having the wrong number of chromosomes is another ...

Due to their critical roles in mitosis, topoisomerases are important chemotherapy ... Much less is known about the role of Topo II in the meiotic cell cycle. We are using a combination of cell biology ...

We identified 53BP1 and USP28 as essential components acting upstream of p53, evoking p21-dependent cell cycle arrest in response not only to centrosome loss, but also to other defects causing ...

In mitosis, two cells called daughter cells are produced, each identical to the parent cell. When looking at cells with a microscope, the length of different stages of the cell cycle can be ...