Methods QL (0.5 mg/mL) was pre-treated in Neonatal Mouse Ventricular Cardiomyocytes (NMVCs) before induction of cardiomyocyte hypertrophy by Angiotensin II (Ang-II). Immunofluorescence staining for ...

Journal of Nuclear Medicine November 2024, jnumed.124.269002; DOI: https://doi.org/10.2967/jnumed.124.269002 ...

Whether this regenerative capacity of human cardiomyocytes is employed in heart failure has been controversial. We determined cardiomyocyte renewal in 52 patients with advanced heart failure, 28 of ...

Fibroblasts are specialized cells in connective tissues that play an important role in wound healing and tissue repair. They produce and organize the so-called extracellular matrix, a network of ...

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment.

Pathological cardiac hypertrophy stands as a pivotal mechanism contributing to diverse cardiovascular diseases, ultimately leading to heart failure. Despite its clinical significance, the intricate ...

This study provides abundant valuable scRNA-Seq data that profiles fibroblasts involved in myocardium and coronary vasculature development. However, the evidence supporting the authors' claims is ...

Heart regeneration is limited in adult mammals but occurs naturally in adult zebrafish through the activation of cardiomyocyte division. Several components of the cardiac injury microenvironment have ...