Antibodies and related products are the fastest growing class of therapeutic agents. By analysing the regulatory approvals of IgG-based biotherapeutic agents in the past 10 years, we can gain ...

Although fewer antibody fragments have entered the clinic ... the action of biological molecules by binding either ligand or receptor, or engaging signaling pathways by cross-linking receptors.

Sanofi's rash of dealmaking has continued with a $2.5 billion tie-up with Chinese cancer immunotherapy biotech Adagene, focused on developing a new generation of safer antibody-based therapies.

These are thyroperoxidase (TPO), thyroglobulin (Tg) and the TSH receptor. Other autoantigens ... in the neonate as a result of a mother with antibodies due to AITD. TPO antibodies (TPOAb) appear ...

Insulin receptor antibodies were present. Treatment with prednisone led to resolution of hypoglycaemia, with no recurrence after 36 months of follow-up. However, 42 months after initial presentation, ...