The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

Bone loss resulting from trauma, fractures, or disease presents a major global health challenge, often leading to long-term ...

LEXINGTON, Mass., Jan. 15, 2025 (GLOBE NEWSWIRE) -- (“Keros” or the “Company”) (Nasdaq: KROS), a clinical-stage ...

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could ...

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could transform treatments for bone ...

I think the authors published similar experiments with BMP pathway mutants. The mad1-2 allele used here as stated below may not be very representative of other BMP pathway mutants. Therefore, it could ...

Keros Therapeutics, Inc. has announced a voluntary halt in dosing for the Tropos trial, a phase 2 clinical trial of ...

Wnt signals in combination with suppressed TGFβ/BMP pathways maintain the hierarchy and procession ... and undertake a progenitor phenotype on exiting the stem cell niche.1,2 Stem cell progeny ...

Regenerative medicine has significantly impacted orthopaedic surgery by introducing biological therapies aimed at repairing, ...

System1’s Andrew Tindall reviews and ranks three fan-made films on the shortlist to run in Doritos Super Bowl spot this year, asking what they tell us about effective advertising.