What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD. The TP53 gene is a gene that is ...

In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

Stanford researchers found that fiber digestion produces compounds that directly alter gene function, potentially preventing ...

Fiber digestion produces short-chain fatty acids like propionate and butyrate, which directly alter gene expression with anti ...

A new study investigates the role of Krüppel-like factor 2 (KLF2, a protein coding gene involved in a variety of regulatory ...

Background Insulin-like growth factor binding protein-3 (IGFBP-3) is known to interfere NF-κB signaling pathway and effectively promotes apoptosis in tumor cells by a variety of mechanisms. Objectives ...

While until recently apoptosis was discussed as being essential for epithelial turnover and tissue homeostasis in the intestinal epithelium, recent data using gene deficient mice have challenged this ...

Shun Chi Sun Laboratory for Traditional Chinese Medicine Research, Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, China Correspondence: Dr. Louis W.C. Chow, Department of Surgery, ...