This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

In contrast, most amino-acid replacements assumed nondamaging ... to avoid possible erroneous annotations of damaging mutations. PolyPhen-2 calculates the naive Bayes posterior probability that ...

Phosphoproteomics unveils the mode of action of clinical ATR inhibitors and explains their synergy with Gemcitabine in ...

(Hint: It’s a lot.) A biggie as of late? Amino acids, which are the building blocks of protein. The 11 amino acids our bodies synthesize are called “nonessential,” but we need nine others (k ...

The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...

This framework combines human expertise with the efficiency of Large Language Models (LLMs) like OpenAI's GPT-3.5 to simplify dataset annotation and model improvement. The iterative approach ensures ...

Excess sugar can lower good and raise bad cholesterol levels. Eating foods high in healthy dietary fat, especially the essential omega-3 fatty acids, is the best way to get your nutrients. However, ...

Beta-lactam antibiotics are the most widely used group of antibiotics, they target the penicillin-binding proteins (PBPs), eventually disrupting the peptidoglycan synthesis. To combat these ...

ShareX is a free and open source program that lets you capture or record any area of your screen and share it with a single press of a key. It also allows uploading images, text or other types of ...