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eLife
16h
TET2-mediated epigenetic modification promotes stress senescence of pancreatic β cells in type 2 diabetes mellitus
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
The EMBO Journal
23h
Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response
Phosphoproteomics unveils the mode of action of clinical ATR inhibitors and explains their synergy with Gemcitabine in ...
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