This pathway includes two isoforms of SphK ... SphK, sphingosine kinase; S1P, sphingosine-1-phosphate; PI3K, phosphoinositide 3-kinase; Akt, protein kinase B; GLUT4, glucose transporter type 4; TNF-α, ...
melittin regulates TLR2, TLR4, CD14, NEMO, and PDGFRβ signaling pathways. Melittin blocks IKKs to prevent ... phospholipase Cγ1; Akt, protein kinase B. The potential protective mechanism of melittin ...
Inositol-requiring enzyme 1 (IRE1) (an upstream regulator of Xbp1) was required for PHLDA3 induction by Tm, whereas other pathways (c-Jun N-terminal ... death depended on serine/threonine protein ...
Diabetes. 2008;57(7):1805-1813. In conclusion, our findings suggest that the increase of glucose uptake by skeletal muscle may contribute to better glycemic control observed in Ad-36-induced ...
Conclusions Construction and analysis of normalised skin transcriptomic compendia can provide useful insights on pathway involvement by SSc subsets and discovering viable biomarkers for a skin ...
Cover picture: Inspired by the Review by Jung-Soon Mo, Hyun Woo Park and Kun-Liang Guan. Illustrated by Sandra Krahl.
Jiyong Liang; Judit Zubovitz; Teresa Petrocelli; Rouslan Kotchetkov; Michael K. Connor; Kathy Han; Jin-Hwa Lee; Sandra Ciarallo; Charles Catzavelos; Richard Beniston ...
This effect was achieved through direct inhibition of nociceptive dorsal root ganglion (DRG) neurons via CD44-dependent pathways. We further purified ... 1:500), CGRP (Cell Signaling Technology, 14959 ...
From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...
Division of Cardiovascular Medicine (R.J., C.M.T.), UMass Chan Medical School; Worcester. Department of Medicine (R.J., C.M.T.), UMass Chan Medical School; Worcester ...