SPR206 is an investigational, intravenously administered next-generation polymyxin that has shown antibiotic activity against MDR Gram-negative pathogens, including carbapenem-resistant ...

Tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of cUTI including acute pyelonephritis (AP) to help patients avoid hospitalizations or reduce ...

There were 4 cases of acute pyelonephritis, 1 of peritonitis and 1 of septicemia of uncertain origin. Four patients died of infection; all 4 were totally bedridden with refractory disease and ...

Fosfomycin disodium is under development for the treatment of complicated urinary tract infections (cUTI), acute pyelonephritis, suspected infection or peri-operative prophylaxis in pediatrics, ...

Spero sought approval of tebipenem on the strength of a phase 3 trial – ADAPT-PO – which showed that the drug was equivalent to standard care with intravenous ertapenem in patients with cUTI ...

A bacterial infection causes acute prostatitis, which occurs suddenly and is short ... The STIs chlamydia and gonorrhea are the most common cause of the condition. Pyelonephritis is an infection in ...

Primary outcome measures Acute kidney injury. Results During a mean follow-up ... of other renal diseases before the index date and if they were diagnosed with pyelonephritis or contrast-induced ...

Dr. Ally Clinical question: Is cefepime-taniborbactam effective in treating complicated urinary tract infections (UTIs)? Background: Complicated UTIs, such as acute pyelonephritis, have a ...

During an acute study in N.G., a solution containing 70 mg of amphotericin B in 1000 ml of 5 per cent dextrose and water was infused at a rate of 1 to 2 ml per minute for four hours. Potassium ...

When seen with granular casts, renal tubule epithelial cells are highly predictive of acute tubular necrosis and can help to exclude prerenal acute kidney injury, seen in postoperative patients ...