Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosysnthesis, CYP17, and blocks the ...
The FDA has approved Johnson & Johnson’s prostate cancer drug Erleada (apalutamide ... Erleada is a successor to J&J’s Zytiga (abiraterone), which has gone off patent in the US and succumbing ...