While the 49ers may rotate in other RBs more than they would have with a player higher on the depth chart starting, chances ...

Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football ...

The San Francisco 49ers released a statement on the passing of Trent Williams’ son. “The 49ers mourn the passing of Trent Williams' son and send him and his family all our love,” the 49ers ...

The 49ers opened the game with a 5-play, 70-yard drive capped by Purdy's 7-yard touchdown pass to Jennings, giving San ...

The Bears (4-8) will visit the 49ers (5-7) Sunday in San Francisco. Here are three things that should increase their chances of winning the game: (1) Establish the run. A productive rushing attack ...

San Francisco 49ers president of football operations/general manager John Lynch issued a statement on linebacker De'Vondre Campbell Sr. The San Francisco 49ers activated LB Dre Greenlaw from the ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly didn't help their playoff chances. They have more than enough injuries ...

On the heels of a third consecutive defeat, the 49ers' place in the 2025 NFL Draft is as important as their rapidly fading spot in the NFC playoff picture. Following San Francisco's 35-10 loss to ...

Rookie Isaac Guerendo has been elevated to the 49ers’ starting running back after San Francisco had to put both Christian McCaffrey and backup Jordan Mason on the IR on the same day. The news of ...

San Francisco 49ers star Christian McCaffrey will not play the rest of the 2024 season. Kyle Shanahan said that Christian McCaffrey did injure his PCL and it is a 6-week recovery. His season now ...

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced. Mason suffered an ankle injury Sunday night against the Buffalo Bills. More News ...

The injury news for the 49ers was twice as bad as expected Monday ... who played in just three games after missing the offseason and training camp with bilateral Achilles tendinitis and had ...