First, the large liver mass, via the reticuloendothelial function of the Kupffer cells, is thought to be capable of sequestering cytotoxic antibodies formed against the graft. The presence of a ...

As noted above, stellate cell activation is the central ... matrix protease activity play an important role in ECM remodeling accompanying fibrosing liver injury (see section on Extracellular ...

Activation of Kupffer cells (liver-resident macrophages ... A notable focus of the review is the role of extracellular vesicles (EVs) in intercellular communication. These nanoscale particles ...

Kupffer cells (KCs) also contribute to this inflammation ... The review examines how alcohol metabolism affects liver function, focusing on the roles of oxidative stress and inflammation in ...

The liver is a large, glandular, vital organ divided into two main lobes with a major role in metabolism ... comprised of hepatocytes, but Kupffer cells, endothelial cells and hepatic ...