Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Transcription factors are proteins that bind to specific ... This study uncovers "guided search" mechanisms, where the 3D architecture of DNA and chromatin—which packages and organizes genetic ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled ...