IN 1914 Walter Jones began the preface to his monograph on nucleic acids with the words, “The nucleic acids constitute what is possibly the best understood field of Physiological Chemistry ...

A nucleic acid is a long molecule made up of smaller molecules called nucleotides. Nucleic acids were discovered in 1868, when twenty-four-year-old Swiss physician Friedrich Miescher isolated a ...

While mRNA vaccines have received intense attention of late, another class of nucleic acid therapeutics has been growing steadily in recent years. Its impact could be equally profound. Nucleic ...

The nucleic acid molecules inherited by the living cell bear the plan of all the cell's protein molecules. It now appears that another kind of nucleic acid plays a key role in translating the plan ...

ALTMANN (1889) suggested the term ‘nucleic acid’ for the acidic substance of high phosphorus content which Miescher had isolated from the nuclei of pus cells and fish spermatozoa. Nucleic acid ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

The sugar-phosphate backbone forms the structural framework of nucleic acids, including DNA and RNA ... in the 5' to 3' direction when the molecule is synthesized. In double-stranded DNA, the ...

Scientists are now finding their own ways to put together nucleotides: to make a powerful new class of medicines based on nucleic acids. “This is true designer therapeutics,” says Brian Brown ...

Hidden within the genetic code lies the "triplet code," a series of three nucleotides that determine a single amino acid. How did scientists discover and unlock this amino acid code? Once the ...

WEST LAFAYETTE, Ind. — A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid ...

Biological cells are incredibly complex mixes of proteins, nucleic acids, lipids and carbohydrates. A model developed by two RIKEN researchers helps explain why components of the same type ...

DNA polymerase (DNAP) is a type of enzyme that is responsible for forming new copies of DNA, in the form of nucleic acid molecules. Nucleic acids are polymers, which are large molecules made up of ...