Macrolides bind reversibly to 23S ribosomal RNA (rRNA) of the 50S subunit of bacterial ribosome inhibiting RNA-dependent protein synthesis. Clindamycin (a lincosamide) at subgrowth inhibitory ...
Clindamycin (as phosphate) 1%; lotion; gel. Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. Clindamycin is predominantly bacteriostatic.