News Medical17d
Mastering colloidal stability in therapeutic protein development
Successful monitoring and characterization methods for colloidal stability involve in situ ... generated throughout elution and nonspecific interactions with resin may also influence native ...
Previously unknown protein interactions may lead to better HIV treatments
The human immune deficiency virus (HIV) first entered public consciousness in the early 1980s, after cases of unfamiliar and ...
The EMBO Journal14d
A split intein and split luciferase-coupled system for detecting protein-protein interactions
The split intein-mediated protein ligation (SIMPL) system for detecting protein-protein interactions has been enhanced by ...
Proteomics method identifies ligand-binding proteins and binding sites in complex systems
In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called ...
EurekAlert!16d
New proteomics method enables sensitive identification of ligand-binding proteins and their binding sites in complex system
Researchers from DICP developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), ...
Chemistry World9d
Debunked dogma: disordered proteins disregard ligands’ chirality
Nevertheless, an increasing number of disordered peptides and proteins have been discovered in recent years. ‘It’s ...
Phys.org29d
Scientists reveal structural link for initiation of protein synthesis in bacteria
"We know there is an interaction between the RNAP, the ribosome, transcription factors, proteins and mRNA," said ... with the recruitment or the stability of the complex." The team developed ...