The following is a summary of “Safety and efficacy of mitapivat in sickle cell disease (RISE UP): results from the phase 2 ...

When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the hemoglobin protein causes the red blood cells to lose oxygen and warp into a sickle shape during periods of ...

A once-groundbreaking sickle cell disease drug — at the center of a $5.4 billion acquisition two years ago — is the subject ...

so they have a mixture of normal and sickle red blood cells. In most situations, individuals who are heterozygous for sickle-cell anemia are phenotypically normal. Under these circumstances ...

CHICAGO (CBS) --The Red Cross ... to collecting blood donations, and being in a city the size of Chicago, the need for blood is constant, particularly for people suffering from sickle cell disease.

But in people with weakened immune systems or sickle cell disease, the virus can lead to more severe symptoms, such as a significant drop in red blood cell production (anemia). If a pregnant woman ...

Sickle cell mostly affects people of black heritage and ethnically-matched blood gives the best treatment. The disease, which is the fastest-growing genetic condition in the UK, causes red blood ...

A campaign has been launched to raise awareness of the urgent need for more black blood donors. It comes as the number of sickle cell anaemia ... The disease causes red blood cells to distort ...

Drug repurposing is the highest priority, as it provides the quickest route from the lab to sickle cell disease patients. The assay depends on having an understanding of the underlying cause of the ...