Yank one into the realm of feasibility and the whole NP edifice collapses, and a scientific revolution rises from the rubble, ...
Although fast kinetics demonstrated that protein folding is not a simple two-state reaction, these experiments did not solve the problem of isolating and characterizing the structures of folding ...
With it he showed it was possible to reverse the protein-folding problem by designing a protein shape and then predicting the ...
An error in protein conformation can lead to disease. What are the genetic and molecular causes for incorrectly formed proteins? molecules. In 1917 the German chemist ...
In 1972, accepting the Nobel Prize for Chemistry, Christian Anfinsen had thrown down the gauntlet for what would become known as “the protein-folding problem.” Proteins are the building blocks ...
The process by which a protein attains its functional structure, known as protein folding, is a complex and ... Jumper’s thesis tackled this problem by leveraging machine learning, marking ...