In particular, these authors describe the imbalance between pro- and anti-inflammatory cytokine activities in rheumatoid joints and how this imbalance favours the induction of autoimmunity ...
Figure 1. Cytokines involved in acute and chronic inflammatory responses (DOI:10.2741/a171). Image Credit: Sino Biological Inc. Disturbance in levels of the key pro-inflammatory cytokines ...
Ultimately, the balance between pro- and anti-inflammatory cytokines determines outcome in lung host defense. As our understanding of the role of cytokines in lung host defense has increased ...
T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...
Because itolizumab acts upstream of pro-inflammatory cytokines, it may have greater potential than therapies targeting single cytokines to shut down runaway immune responses. In 2013, itolizumab ...
Hence, it is the balance between pro- and anti-inflammatory cytokines that dictates outcome in lung host defense. Schematic depicting the role of cytokines and lung cells in innate immunity ...