But up to 70 percent of people taking the drugs, such as esomeprazole (Nexium) and omeprazole (Prilosec and generic), might not need such strong medication, research has found. Quitting heartburn ...

PPIs are among the highest-selling classes of drugs in the U.S., with $9.5 billion in sales last year, and one of them, Nexium ... Three—omeprazole (Prilosec, Prilosec OTC), lansoprazole ...

Drugs like Nexium, Prevacid, and Prilosec are called proton pump inhibitors, or PPIs, and they've been linked to a bigger risk for dementia. PPIs reduce the amount of acid that your stomach makes.