Streptococcus pneumoniae remains an important pathogen despite licensure of a seven-valent pneumococcal protein conjugate vaccine. As a result, serotyping strains remains of paramount importance ...
Ibudilast is under clinical development by MediciNova and currently in Phase II for Coronavirus Disease 2019 (COVID-19) Pneumonia.
researcher Oswald Avery and his colleagues at the Rockefeller University in New York were performing detailed analyses of the pneumococcal cell capsule and the role of this capsule in infections.
Capsular locus for the 91 pneumococcal serotypes is between 10 and 30 kb in length and is flanked by the conserved dexB and aliA genes. The marked heterogeneity within the capsular operon has been ...